[Significance of phosphate in internal medicine]. / Phosphat in der Inneren Medizin.
Dtsch Med Wochenschr
; 149(3): 93-100, 2024 Feb.
Article
en De
| MEDLINE
| ID: mdl-38262403
ABSTRACT
Phosphate is essential for bone metabolism and for energy provision. Phosphate homeostasis is achieved by hormonal feedback mechanisms, predominantly parathyroid hormone, fibroblast growth factor 23 and calcitriol, with renal phosphate absorption taking on a special role. Although even large deviations from the serum normal range are rarely symptomatic, the health consequences can be significant. Essentially, the clinically relevant disturbances in phosphate balance can be attributed to three mechanisms 1. shifts of phosphate between the extracellular space and the cytosol; 2. inadequate phosphate reabsorption in the kidney; 3. decreased intestinal phosphate absorption. Knowledge of physiology enables diagnosis and therapy of phosphate disorders.
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Bases de datos:
MEDLINE
Asunto principal:
Fosfatos
/
Medicina Interna
Límite:
Humans
Idioma:
De
Revista:
Dtsch Med Wochenschr
Año:
2024
Tipo del documento:
Article