Histone methylation readers MRG1/2 interact with PIF4 to promote thermomorphogenesis in Arabidopsis.
Cell Rep
; 43(2): 113726, 2024 Feb 27.
Article
en En
| MEDLINE
| ID: mdl-38308844
ABSTRACT
Warm ambient conditions induce thermomorphogenesis and affect plant growth and development. However, the chromatin regulatory mechanisms involved in thermomorphogenesis remain largely obscure. In this study, we show that the histone methylation readers MORF-related gene 1 and 2 (MRG1/2) are required to promote hypocotyl elongation in response to warm ambient conditions. A transcriptome sequencing analysis indicates that MRG1/2 and phytochrome interacting factor 4 (PIF4) coactivate a number of thermoresponsive genes, including YUCCA8, which encodes a rate-limiting enzyme in the auxin biosynthesis pathway. Additionally, MRG2 physically interacts with PIF4 to bind to thermoresponsive genes and enhances the H4K5 acetylation of the chromatin of target genes in a PIF4-dependent manner. Furthermore, MRG2 competes with phyB for binding to PIF4 and stabilizes PIF4 in planta. Our study indicates that MRG1/2 activate thermoresponsive genes by inducing histone acetylation and stabilizing PIF4 in Arabidopsis.
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Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Fitocromo
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Arabidopsis
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Proteínas de Arabidopsis
Idioma:
En
Revista:
Cell Rep
Año:
2024
Tipo del documento:
Article