Your browser doesn't support javascript.
loading
Workflow to facilitate the detection of new psychoactive substances and drugs of abuse in influent urban wastewater.
Bade, Richard; van Herwerden, Denice; Rousis, Nikolaos; Adhikari, Sangeet; Allen, Darren; Baduel, Christine; Bijlsma, Lubertus; Boogaerts, Tim; Burgard, Dan; Chappell, Andrew; Driver, Erin M; Sodre, Fernando Fabriz; Fatta-Kassinos, Despo; Gracia-Lor, Emma; Gracia-Marín, Elisa; Halden, Rolf U; Heath, Ester; Jaunay, Emma; Krotulski, Alex; Lai, Foon Yin; Löve, Arndís Sue Ching; O'Brien, Jake W; Oh, Jeong-Eun; Pasin, Daniel; Castro, Marco Pineda; Psichoudaki, Magda; Salgueiro-Gonzalez, Noelia; Gomes, Cezar Silvino; Subedi, Bikram; Thomas, Kevin V; Thomaidis, Nikolaos; Wang, Degao; Yargeau, Viviane; Samanipour, Saer; Mueller, Jochen.
Afiliación
  • Bade R; Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, Queensland 4102, Australia. Electronic address: r.bade@uq.edu.au.
  • van Herwerden D; Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, the Netherlands.
  • Rousis N; Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, Queensland 4102, Australia.
  • Adhikari S; School of Sustainable Engineering and Built Environment, Arizona State University, Tempe, AZ 85281, United States; Biodesign Center for Environmental Health Engineering, Biodesign Institute, Arizona State University, 1001 S. McAllister Ave., Tempe, AZ 85281, United States.
  • Allen D; Royal Brisbane and Women's Hospital, Herston, QLD 4029, Australia.
  • Baduel C; Université Grenoble Alpes, CNRS, IRD, Grenoble INP, Institute of Environmental Geosciences (IGE), Grenoble, France.
  • Bijlsma L; Environmental and Public Health Analytical Chemistry, Research Institute for Pesticides and Water, University Jaume I, Avda, Sos Baynat s/n, E-12071 Castellón, Spain.
  • Boogaerts T; Toxicological Centre, Department of Pharmaceutical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
  • Burgard D; Department of Chemistry and Biochemistry, University of Puget Sound, Tacoma, WA 98416, United States.
  • Chappell A; Institute of Environmental Science and Research Limited (ESR), Christchurch Science Centre, 27 Creyke Road, Ilam, Christchurch 8041, New Zealand.
  • Driver EM; Biodesign Center for Environmental Health Engineering, Biodesign Institute, Arizona State University, 1001 S. McAllister Ave., Tempe, AZ 85281, United States.
  • Sodre FF; Institute of Chemistry, University of Brasília, Brasília, DF 70910-000, Brazil.
  • Fatta-Kassinos D; Nireas-International Water Research Centre and Department of Civil and Environmental Engineering, University of Cyprus, P.O. Box 20537, 1678 Nicosia, Cyprus.
  • Gracia-Lor E; Department of Analytical Chemistry, Faculty of Chemistry, Complutense University of Madrid, Avenida Complutense s/n, 28040 Madrid, Spain.
  • Gracia-Marín E; Environmental and Public Health Analytical Chemistry, Research Institute for Pesticides and Water, University Jaume I, Avda, Sos Baynat s/n, E-12071 Castellón, Spain.
  • Halden RU; School of Sustainable Engineering and Built Environment, Arizona State University, Tempe, AZ 85281, United States; Biodesign Center for Environmental Health Engineering, Biodesign Institute, Arizona State University, 1001 S. McAllister Ave., Tempe, AZ 85281, United States; OneWaterOneHealth, Arizona
  • Heath E; Jozef Stefan Institute and International Postgraduate School Jozef Stefan, Jamova 39, 1000 Ljubljana, Slovenia.
  • Jaunay E; Health and Biomedical Innovation, UniSA: Clinical and Health Sciences, University of South Australia, Adelaide 5001, South Australia, Australia.
  • Krotulski A; Center for Forensic Science Research and Education, Fredric Rieders Family Foundation, Willow Grove, PA 19090, United States.
  • Lai FY; Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences (SLU), SE-75007 Uppsala, Sweden.
  • Löve ASC; University of Iceland, Department of Pharmacology and Toxicology, Hofsvallagata 53, 107 Reykjavik, Iceland; University of Iceland, Faculty of Pharmaceutical Sciences, Hofsvallagata 53, 107 Reykjavik, Iceland.
  • O'Brien JW; Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, Queensland 4102, Australia; Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, the Netherlands.
  • Oh JE; Department of Civil and Environmental Engineering, Pusan National University, Jangjeon-dong, Geumjeong-gu, Busan 46241, Republic of Korea.
  • Pasin D; Forensic Laboratory Division, San Francisco Office of the Chief Medical Examiner, 1 Newhall St, San Francisco, CA 94124, United States.
  • Castro MP; Department of Chemical Engineering, McGill University, Montreal, QC, Canada.
  • Psichoudaki M; Nireas-International Water Research Centre and Department of Civil and Environmental Engineering, University of Cyprus, P.O. Box 20537, 1678 Nicosia, Cyprus.
  • Salgueiro-Gonzalez N; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Department of Environmental Health Sciences, Via Mario Negri 2, 20156 Milan, Italy.
  • Gomes CS; Laboratory of Forensic Chemistry, Brazilian Federal Police, PB, Brazil.
  • Subedi B; Department of Chemistry, Murray State University, Murray, KY 42071-3300, United States.
  • Thomas KV; Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, Queensland 4102, Australia.
  • Thomaidis N; Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.
  • Wang D; College of Environmental Science and Engineering, Dalian Maritime University, No. 1 Linghai Road, Dalian 116026, PR China.
  • Yargeau V; Department of Chemical Engineering, McGill University, Montreal, QC, Canada.
  • Samanipour S; Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, the Netherlands; UvA Data Science Center, University of Amsterdam, the Netherlands.
  • Mueller J; Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, 20 Cornwall Street, Woolloongabba, Queensland 4102, Australia.
J Hazard Mater ; 469: 133955, 2024 May 05.
Article en En | MEDLINE | ID: mdl-38457976
ABSTRACT
The complexity around the dynamic markets for new psychoactive substances (NPS) forces researchers to develop and apply innovative analytical strategies to detect and identify them in influent urban wastewater. In this work a comprehensive suspect screening workflow following liquid chromatography - high resolution mass spectrometry analysis was established utilising the open-source InSpectra data processing platform and the HighResNPS library. In total, 278 urban influent wastewater samples from 47 sites in 16 countries were collected to investigate the presence of NPS and other drugs of abuse. A total of 50 compounds were detected in samples from at least one site. Most compounds found were prescription drugs such as gabapentin (detection frequency 79%), codeine (40%) and pregabalin (15%). However, cocaine was the most found illicit drug (83%), in all countries where samples were collected apart from the Republic of Korea and China. Eight NPS were also identified with this protocol 3-methylmethcathinone 11%), eutylone (6%), etizolam (2%), 3-chloromethcathinone (4%), mitragynine (6%), phenibut (2%), 25I-NBOH (2%) and trimethoxyamphetamine (2%). The latter three have not previously been reported in municipal wastewater samples. The workflow employed allowed the prioritisation of features to be further investigated, reducing processing time and gaining in confidence in their identification.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Contaminantes Químicos del Agua / Drogas Ilícitas País/Región como asunto: Asia Idioma: En Revista: J Hazard Mater Asunto de la revista: SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Contaminantes Químicos del Agua / Drogas Ilícitas País/Región como asunto: Asia Idioma: En Revista: J Hazard Mater Asunto de la revista: SAUDE AMBIENTAL Año: 2024 Tipo del documento: Article