Long-term outcome of combined radiologic and surgical strategy for the management of biliary complications after pediatric liver transplantation.
BMC Res Notes
; 17(1): 86, 2024 Mar 20.
Article
en En
| MEDLINE
| ID: mdl-38509599
ABSTRACT
OBJECTIVES:
We aimed to analyze the risk factors for management failure of BC after pediatric liver transplantation (pLT) by retrospectively analyzing primary pLT performed between 1997 and 2018 (n = 620 patients).RESULTS:
In all, 117/620 patients (19%) developed BC. The median (range) follow-up was 9 (1.4-21) years. Patient survival at 1, 5 and 10 years was 88.9%, 85.7%, 84.4% and liver graft survival was 82.4%, 77.4%, and 74.3% respectively. Graft not patient survival was impaired by BC (p = 0.01). Multivariate analysis identified the number of dilatation courses > 2 (p = 0.008), prolonged cold ischemia time (p = 0.004), anastomosed multiple biliary ducts (p = 0.019) and hepatic artery thrombosis (p = 0.01) as factors associated with impaired graft survival. The number of dilatation courses > 2 (p < 0.001) and intrahepatic vs anastomotic stricture (p = 0.014) were associated with management failure. Thus, repeated (> 2) radiologic dilatation courses are associated with impaired graft survival and management failure. Overall, graft but not patient survival was impaired by BC.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Trasplante de Hígado
/
Hepatopatías
Límite:
Child
/
Humans
Idioma:
En
Revista:
BMC Res Notes
Año:
2024
Tipo del documento:
Article
País de afiliación:
Francia