Synthetic Chameleon Turns into Oximes, Nitrones, and Hydroxylamines when Exposed to Blue Light.
ACS Omega
; 9(12): 14262-14268, 2024 Mar 26.
Article
en En
| MEDLINE
| ID: mdl-38559917
ABSTRACT
A metal-free, user-friendly photochemical transformation of nitroalkanes to oximes, nitrones, and hydroxylamines has been developed. The visible-light-induced reactions are catalyzed by the readily available photoredox organocatalyst 4CzIPN and use inexpensive amines as reductants. Broad in scope and tolerant of multiple functional groups and heterocycles, the transformation proceeds under mild conditions. Its synthetic potential was demonstrated in the formal total synthesis of amathaspiramide F. A basic insight into the reaction mechanism was gained with the help of an NMR study.
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MEDLINE
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Revista:
ACS Omega
Año:
2024
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Article
País de afiliación:
Eslovaquia