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Programmatic considerations and evidence gaps for chikungunya vaccine introduction in countries at risk of chikungunya outbreaks: Stakeholder analysis.
Auzenbergs, Megan; Maure, Clara; Kang, Hyolim; Clark, Andrew; Brady, Oliver; Sahastrabuddhe, Sushant; Abbas, Kaja.
Afiliación
  • Auzenbergs M; London School of Hygiene and Tropical Medicine, London, United Kingdom.
  • Maure C; International Vaccine Institute, Seoul, South Korea.
  • Kang H; London School of Hygiene and Tropical Medicine, London, United Kingdom.
  • Clark A; London School of Hygiene and Tropical Medicine, London, United Kingdom.
  • Brady O; London School of Hygiene and Tropical Medicine, London, United Kingdom.
  • Sahastrabuddhe S; International Vaccine Institute, Seoul, South Korea.
  • Abbas K; London School of Hygiene and Tropical Medicine, London, United Kingdom.
PLoS Negl Trop Dis ; 18(4): e0012075, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38574163
ABSTRACT
Chikungunya can have longstanding effects on health and quality of life. Alongside the recent approval of the world's first chikungunya vaccine by the US Food and Drug Administration in November 2023 and with new chikungunya vaccines in the pipeline, it is important to understand the perspectives of stakeholders before vaccine rollout. Our study aim is to identify key programmatic considerations and gaps in Evidence-to-Recommendation criteria for chikungunya vaccine introduction. We used purposive and snowball sampling to identify global, national, and subnational stakeholders from outbreak prone areas, including Latin America, Asia, and Africa. Semi-structured in-depth interviews were conducted and analysed using qualitative descriptive methods. We found that perspectives varied between tiers of stakeholders and geographies. Unknown disease burden, diagnostics, non-specific disease surveillance, undefined target populations for vaccination, and low disease prioritisation were critical challenges identified by stakeholders that need to be addressed to facilitate rolling out a chikungunya vaccine. Future investments should address these challenges to generate useful evidence for decision-making on new chikungunya vaccine introduction.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas / Fiebre Chikungunya Límite: Humans Idioma: En Revista: PLoS Negl Trop Dis Asunto de la revista: MEDICINA TROPICAL Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vacunas / Fiebre Chikungunya Límite: Humans Idioma: En Revista: PLoS Negl Trop Dis Asunto de la revista: MEDICINA TROPICAL Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido