Association between the geriatric nutritional risk index and clinical outcomes among peritoneal dialysis patients: A meta-analysis.
Medicine (Baltimore)
; 103(18): e38048, 2024 May 03.
Article
en En
| MEDLINE
| ID: mdl-38701289
ABSTRACT
BACKGROUND:
To identify the relationship between the geriatric nutritional risk index (GNRI) and clinical outcomes in patients receiving peritoneal dialysis (PD).METHODS:
The PubMed, EBASE, Web of Science and CNKI databases were searched for available studies up to December 25, 2023. The primary outcome was all-cause mortality, and the secondary outcomes included the incidence of PD dropout, major adverse cardiac and cerebrovascular events (MACCEs), technique failure and peritonitis. Hazard ratios (HRs) and 95% confidence intervals (CIs) were combined to evaluate the predictive value of the GNRI for the occurrence of the above endpoints.RESULTS:
Ten cohort studies with 3897 patients were included. The pooled results demonstrated that a lower GNRI was significantly associated with a greater incidence of all-cause mortality (HRâ =â 0.71, 95% CI 0.55-0.91; Pâ =â .007). In addition, a decreased GNRI predicted the occurrence of dropout from PD (HRâ =â 0.971, 95% CI 0.945-0.998, Pâ =â .034) and MACCE (HRâ =â 0.95, 95% CI 0.92-0.98, Pâ =â .001). However, no significant associations of the GNRI with technique failure (Pâ =â .167) or peritonitis (Pâ =â .96) were observed.CONCLUSION:
A low GNRI is significantly associated with poor clinical outcomes and might serve as a novel and valuable prognostic indicator among PD patients.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Diálisis Peritoneal
Límite:
Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2024
Tipo del documento:
Article