Affinity alone does not drive long-lived plasma cell differentiation.

McDougal, Courtney E; Pepper, Marion

McDougal, Courtney E; Pepper, Marion.

Afiliación

McDougal CE; Department of Immunology, University of Washington, Seattle, WA, USA.
Pepper M; Department of Immunology, University of Washington, Seattle, WA, USA.

Immunol Cell Biol ; 102(7): 532-534, 2024 Aug.

Article en En | MEDLINE | ID: mdl-38715314

ABSTRACT

ABSTRACT

Long-lived plasma cells are important for preventing infection by maintaining baseline antibody titers. However, the cues leading to plasma cell differentiation remain unclear. In this article, we discuss recent work assessing the role of affinity on plasma cell differentiation.

Asunto(s)

Diferenciación Celular; Células Plasmáticas; Animales; Humanos; Afinidad de Anticuerpos/inmunología; Diferenciación Celular/inmunología; Células Plasmáticas/inmunología

Palabras clave

Humoral immunity; longlived plasma cells; memory B cells

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Células Plasmáticas / Diferenciación Celular Límite: Animals / Humans Idioma: En Revista: Immunol Cell Biol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

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