[Association between ambient air pollution and biological aging among the middle-aged and older adults: a systematic review].
Zhonghua Yu Fang Yi Xue Za Zhi
; 58(5): 599-607, 2024 May 06.
Article
en Zh
| MEDLINE
| ID: mdl-38715498
ABSTRACT
Objective:
To summarize and elucidate the impact of ambient air pollution on biological aging among middle-aged and older adults.Methods:
"Air pollution""Biological age""Epigenetic age""Biological aging"and"Epigenetic aging", as well as specific names of air pollutants and biological age were used as search keywords. This study searched the databases of PubMed and Web of Science for eligible English articles and CNKI, CQVIP, Wanfang, CBM, CSTP and other Chinese databases for eligible Chinese articles from inception until June 30, 2023. The language was limited to Chinese and English.Results:
Among the 14 included articles, five studies investigated the impact of air pollution on DNA methylation age using different algorithms, while six studies explored the relationship between air pollutants and telomere length. Six studies focused on frailty as an outcome, and an additional study revealed the relationship between fine particulate matter (PM2.5) and its components with composite indicator age (KDM age). The results indicated that, although different forms of biological ages were susceptible to different ambient air pollutants at different degrees, previous studies had consistently found that the increased levels of PM2.5 and one of its major components, black carbon (BC), could significantly accelerate the biological aging of middle-aged and older adults. Similar trends were observed with nitrogen oxides (NOx) and ozone (O3) but with relatively limited evidence.Conclusion:
Major air pollutants could accelerate the biological aging of middle-aged and older adults.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Envejecimiento
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Contaminantes Atmosféricos
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Contaminación del Aire
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Material Particulado
Límite:
Aged
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Humans
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Middle aged
Idioma:
Zh
Revista:
Zhonghua Yu Fang Yi Xue Za Zhi
Año:
2024
Tipo del documento:
Article
País de afiliación:
China