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Destroyed lung contributes to the recurrence of hemoptysis after bronchial artery embolization in patients with post-tuberculosis bronchiectasis.
Wang, Le-Le; Lu, Hai-Wen; Li, Ling-Ling; Jiang, Sen; Xu, Jin-Fu.
Afiliación
  • Wang LL; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Lu HW; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
  • Li LL; Department of Interventional Radiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
  • Jiang S; Department of Interventional Radiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China. Electronic address: jasfly77@vip.163.com.
  • Xu JF; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China; Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China. Electronic address: jfxu@tongji.edu.cn.
J Infect Public Health ; 17(7): 102446, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38820899
ABSTRACT

BACKGROUND:

Bronchiectasis has high rates of hemoptysis and recurrent hemoptysis, which is inconsistent among various etiologies. Idiopathic bronchiectasis and post-tuberculous bronchiectasis are two important etiologies in China, but the differences in clinical features and risk factors of recurrent hemoptysis have not been elucidated.

METHODS:

Patients hospitalized for idiopathic bronchiectasis or post-tuberculosis bronchiectasis were included. Patients were followed up for at least 24 months post-BAE. Demographic characteristics and clinical data were collected and analyzed between idiopathic bronchiectasis and post-tuberculosis bronchiectasis. Based on the outcomes of recurrent severe hemoptysis in patients with post-tuberculosis bronchiectasis, Cox regression models were used to identify risk factors for recurrence.

RESULTS:

Among 417 patients including 352 idiopathic bronchiectasis and 65 post-tuberculous bronchiectasis, 209 (50.1%) were females. Compared with the idiopathic group, the proportion of patients with female (54.5% vs. 26.2%, p < 0.001), with sputum (79.5% vs. 36.9%, p < 0.001), isolation of Pseudomonas aeruginosa (28.7% vs. 7.7%, p < 0.001), and the number of bronchiectatic lobes≥ 3(98.3% vs 50.8%, p < 0.001) were lower, and the proportion of destroyed lung (4.5% vs. 26.6%, p < 0.001) and recurrence of severe hemoptysis (22.4% vs. 41.5%, p = 0.001) were higher in the post-tuberculous group. Among patients with post-tuberculosis bronchiectasis, destroyed lung [HR 3.2(1.1,9.1), p = 0.026] and abnormal esophageal proper artery [HR 2.8(1.1,7.0), p = 0.032] were two independent risk factors for the recurrence of hemoptysis.

CONCLUSIONS:

The recurrence rate of severe hemoptysis in patients with post-tuberculous bronchiectasis receiving BAE is high, and the proper esophageal artery should be actively evaluated and standardized treatment should be given.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Recurrencia / Arterias Bronquiales / Bronquiectasia / Embolización Terapéutica / Hemoptisis Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: J Infect Public Health Asunto de la revista: DOENCAS TRANSMISSIVEIS / SAUDE PUBLICA Año: 2024 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Recurrencia / Arterias Bronquiales / Bronquiectasia / Embolización Terapéutica / Hemoptisis Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Asia Idioma: En Revista: J Infect Public Health Asunto de la revista: DOENCAS TRANSMISSIVEIS / SAUDE PUBLICA Año: 2024 Tipo del documento: Article País de afiliación: China