Decoding Gray Matter Involvement in Multiple Sclerosis via Imaging.
Neuroimaging Clin N Am
; 34(3): 453-468, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38942527
ABSTRACT
Multiple sclerosis (MS) is increasingly understood not only as a white matter disease but also involving both the deep and cortical gray matter (GM). GM pathology in people with MS (pwMS) includes the presence of lesions, leptomeningeal inflammation, atrophy, altered iron concentration, and microstructural changes. Studies using 7T and 3T MR imaging with optimized protocols established that GM damage is a principal driver of disease progression in pwMS. Future work is needed to incorporate the assessment of these GM imaging biomarkers into the clinical workup of pwMS and the assessment of treatment efficacy.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
/
Neuroimagen
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Sustancia Gris
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Esclerosis Múltiple
Límite:
Humans
Idioma:
En
Revista:
Neuroimaging Clin N Am
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
NEUROLOGIA
Año:
2024
Tipo del documento:
Article