[Novel N-pyrazolylsalicylamides with antifungal activity]. / Nuove N-pirazolilsalicilammidi ad attività antifungina.

ABSTRACT

A number of new N-pyrazolylsalicylamides were prepared by fusion of phenyl salicylate and aminopyrazoles. The condensation reaction is influenced by the substitution at the C-4 position of the aminopyrazole. All the substances obtained were tested for antifungal activity against Cryptococcus neoformans and Candida albicans. It was found that their fungitoxicity is dependent on the structural feature.