[Effect of street noise on blood catecholamines, cyclic AMP and various cardiovascular and metabolic functions in a group of subjects with untreated essential hypertension]. / Effetti del rumore stradale sulle catecolamine ematiche, sul cAMP e su alcune funzioni cardio-vascolari e metaboliche in un gruppo di soggetti ipertesi essenziali non trattati.

ABSTRACT

The effect of road noise on blood catecholamines, cAMP and certain cardiovascular and metabolic parameters was studied in a group of young untreated essential hypertensives. It was found that the 10' stimulus increased both systolic and diastolic pressure values. Blood catecholamines rose only after 5'. The most significant increase was in adrenaline as opposed to noradrenaline and dopamine. Significant changes were noted in cAMP and triacylglycerols (10' and 15' after commencement of the stimulus respectively). Comparison with previous results in normotensives suggested that the catecholamine response to stress is primarily alpha-receptorial when blood pressure is normal and beta-adrenergic in hypertension.