The use of the rat in the experimental investigation of the porphyrias.
J S Afr Vet Assoc
; 49(3): 249-51, 1978 Sep.
Article
en En
| MEDLINE
| ID: mdl-745206
ABSTRACT
The patterns of urinary porphyria excretion and hepatic porphyrin accumulation in hexachlorobenzene-treated rats is similar to that observed in overt porphyria cutanea tarda and may be attributed to a decrease in activity of hepatic uroporphyrinogen (UROGEN) decarboxylase. The 3.5 diethoxycarbonyl-1,4-dihydrocollidine (DDC)-treated rat has been evaluated as a model to test the porphyrinogenicity of drugs.
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Bases de datos:
MEDLINE
Asunto principal:
Porfirias
Límite:
Animals
Idioma:
En
Revista:
J S Afr Vet Assoc
Año:
1978
Tipo del documento:
Article