Repermeation of partially embolized cerebral arteriovenous malformations: a clinical, radiologic, and histologic study.
AJNR Am J Neuroradiol
; 17(7): 1323-31, 1996 Aug.
Article
en En
| MEDLINE
| ID: mdl-8871719
ABSTRACT
PURPOSE:
To describe the pattern and time course of embolization-related tissue lesions and repermeation of the intranidal cast after endovascular embolization of cerebral arteriovenous malformations (AVMs) with N-butyl cyanoacrylate (NBCA).METHODS:
We retrospectively reviewed the records of 26 patients who were treated by endovascular embolization with NBCA and subsequent surgical extirpation to look for embolization-related tissue lesions and repermeation of the cast. A residual flow through the malformation was identified on preoperative angiograms in every case.RESULTS:
Pattern and time course of embolization-related tissue lesions were typical. Until 3 months after embolization, repermeation of embolized structures did not occur. In contrast, repermeation was found in every patient who had surgery later than 3 months after the first embolization (n = 13; 50%). In these cases, histologic examination of the resected nidus disclosed capillary structures inside the lumen of embolized vessels. Capillaries were traced immunohistochemically with antibodies against membrane-bound factor VIII. No parameter other than the interval between the first embolization and surgery was found to relate to the repermeation of the cast.CONCLUSION:
Intranidal recapillarization can occur later than 3 months after the first embolization with NBCA if total and solid casting of the nidus was not accomplished.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Reperfusión
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Malformaciones Arteriovenosas Intracraneales
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Embolización Terapéutica
Tipo de estudio:
Observational_studies
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Prognostic_studies
Límite:
Adolescent
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Adult
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Child
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
AJNR Am J Neuroradiol
Año:
1996
Tipo del documento:
Article