Vulvar vitiligo-like depigmentation and multiple halos of hypomelanosis at the trunk following treatment with imiquimod 5% cream for vulvar condylomata: casual or related events?
An. bras. dermatol
; 89(5): 806-807, Sep-Oct/2014. graf
Article
em En
| LILACS
| ID: lil-720779
Biblioteca responsável:
BR1.1
ABSTRACT
A 25-year-old Caucasian female with multiple genital warts involving the vulvar area was treated with imiquimod 5% cream. During follow-up the patient developed areas of hypopigmentation at the site of application of imiquimod cream and areas of hypomelanosis around multiple preexisting nevi of the trunk. At 18 months follow-up genital depigmentation persisted and halo nevi of the trunk were still present. Different mechanisms of imiquimod-induced depigmentation have been reported. Halo nevi are considered expression of an autoimmune response. In the case presented here, it might be conceivable that both vitiligo-like depigmentation at the site of application and halo of hypomelanosis around melanocytic nevi have been induced by the same immunologic mechanism elicited by topical application of imiquimod.
Palavras-chave
Texto completo:
1
Bases de dados:
LILACS
Assunto principal:
Vitiligo
/
Doenças da Vulva
/
Condiloma Acuminado
/
Adjuvantes Imunológicos
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Nevo com Halo
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Aminoquinolinas
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
An. bras. dermatol
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Itália