Genetic and environmental influences on waist-to-hip ratio and waist circumference in an older Swedish twin population.
Int J Obes Relat Metab Disord
; 23(5): 449-55, 1999 May.
Article
em En
| MEDLINE
| ID: mdl-10375046
ABSTRACT
OBJECTIVE:
To investigate the genetic and environmental influences on waist-to-hip ratio (WHR) and waist circumference (WC) measurements in males and females.DESIGN:
Measurements taken from 1989-1991 as part of The Swedish Adoption/Twin Study of Aging (SATSA) were used for analysis. The SATSA sample contains both twins reared together as well as twins reared apart.SUBJECTS:
322 pairs of twins (50 identical, 82 fraternal male pairs and 67 identical, 123 fraternal female pairs); age range 45-85y (average age, 65y). MEASUREMENTS Waist-to-hip ratio (WHR), waist circumference (WC) and body mass index (BMI).RESULTS:
In males, additive genetic effects were found to account for 28% of the variance in WHR and 46% of the variance in WC. In females, additive genetic effects were found to account for 48% of the variance in WHR and 66% of the variance in WC. The remaining variance in males was attributed to unique environmental effects (WHR, 72%; WC, 54%) and in females the remaining variance was attributed to unique environmental effects (WHR, 46%; WC, 34%) and age (WHR, 6%). When BMI was added into these models it accounted for a portion of the genetic and environmental variance in WHR, and over half of the genetic and environmental variance in WC.CONCLUSION:
There are both genetic and environmental influences on WHR and WC, independent of BMI in both males and females, and the differences between the sexes are significantly different.
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Bases de dados:
MEDLINE
Assunto principal:
Constituição Corporal
/
Meio Ambiente
/
Obesidade
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Int J Obes Relat Metab Disord
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Estados Unidos