Are mutations in the cystic fibrosis gene important in chronic pancreatitis?
Surg Clin North Am
; 79(4): 723-31, viii, 1999 Aug.
Article
em En
| MEDLINE
| ID: mdl-10470322
ABSTRACT
The leading causes of chronic pancreatitis are alcohol and idiopathic pancreatitis. The importance of genetic factors in chronic pancreatitis has been uncertain. Recently, however, it was learned that many patients with idiopathic chronic pancreatitis have mutations of the cystic fibrosis gene. This article reviews the evidence that links mutations of this gene to unexplained pancreatitis, and discusses the implications of this for the evaluation, pathogenesis, classification, and possible prevention of pancreatitis.
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Bases de dados:
MEDLINE
Assunto principal:
Pancreatite
/
Regulador de Condutância Transmembrana em Fibrose Cística
/
Mutação
Limite:
Humans
Idioma:
En
Revista:
Surg Clin North Am
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Estados Unidos