Trisomy 21 associated with ovarian dysgerminoma.
Gynecol Oncol
; 74(3): 512-4, 1999 Sep.
Article
em En
| MEDLINE
| ID: mdl-10479522
ABSTRACT
A 13-year-old G(0)P(0) white female with trisomy 21 presented with a complex pelvic mass. She underwent resection of the mass and complete staging for what was found to be a stage IIIC completely resected dysgerminoma. She was treated with three cycles of bleomycin, etoposide, and cisplatin chemotherapy and remains free of disease 1 year later. This association is presented as a rare case that may illustrate the relative increase in germ cell neoplasms in female patients with Down's syndrome. While the association of seminoma with Down's syndrome has been documented in a number of cases in males, the female counterpart of this tumor, dysgerminoma, in trisomy 21 has been reported quite infrequently. The potential for germ cell tumors in both male and female trisomy 21 is therefore illustrated.
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Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Ovarianas
/
Síndrome de Down
/
Disgerminoma
Tipo de estudo:
Risk_factors_studies
Limite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Gynecol Oncol
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Estados Unidos