Combined electroconvulsive-clozapine therapy.
Clin Neuropharmacol
; 23(1): 14-6, 2000.
Article
em En
| MEDLINE
| ID: mdl-10682225
ABSTRACT
We reviewed 36 reported psychiatric patients who were treated with a combination of electroconvulsive therapy (ECT) and clozapine. The indication of the ECT-clozapine treatment was resistance to classical antipsychotic agents, clozapine, or ECT alone. Sixty-seven percent of the patients benefited from the combined treatment. In most of the patients, the combined treatment was safe and well tolerated. Adverse reactions occurred in 16.6% of the patients and included prolonged ECT-induced seizures (one case), supraventricular (one case) and sinus tachycardia, and blood pressure elevation. It seems that combined ECT-clozapine treatment is effective and safe. This strategy may be a therapeutic option in treatment-resistant patients.
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Bases de dados:
MEDLINE
Assunto principal:
Transtornos Psicóticos
/
Antipsicóticos
/
Clozapina
/
Eletroconvulsoterapia
Tipo de estudo:
Systematic_reviews
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Clin Neuropharmacol
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Israel