Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls.
Nat Genet
; 28(2): 126-8, 2001 Jun.
Article
em En
| MEDLINE
| ID: mdl-11381257
ABSTRACT
A genetic association between NOTCH4 and schizophrenia has previously been proposed. Unsing all markers previously shown to be associated, we found no evidence for such in three independent family-based samples (n=519 parent-offspring trios), and a case-control sample derived from the same ethnic background as the original observation. These data strongly suggest that NOTCH4 is not a significant susceptibility allele for schizophrenia.
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Bases de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Desequilíbrio de Ligação
/
Proteínas Proto-Oncogênicas
/
Receptores de Superfície Celular
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Nat Genet
Assunto da revista:
GENETICA MEDICA
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Estados Unidos