Uveal melanomas with optic nerve extension: report of two cases diagnosed by transvitreal biopsy, one of them with a multicentric tumour.
Acta Ophthalmol Scand
; 79(3): 322-5, 2001 Jun.
Article
em En
| MEDLINE
| ID: mdl-11401650
ABSTRACT
PURPOSE:
To report two cases of invasive uveal melanomas, one of which showed multifocality.METHODS:
Clinical examination, ultrasonography, colour Doppler analysis, cytological and histopathological evaluations.RESULTS:
Transvitreal biopsy (case 1) or fine needle aspiration biopsy (FNAB) (case 2) revealed malignant melanomas in both patients. Light microscopy and immunohistochemical examinations substantiated the diagnosis of mixed cell type melanomas. In addition, one patient had a multifocal melanoma with papilloedema and colour Doppler findings suggestive of optic disc involvement.CONCLUSION:
Transvitreal biopsy for histology or cytology is a reliable procedure to obtain an accurate diagnosis without delay of a lesion adjacent to the optic nerve head. In our two cases the biopsy findings led to enucleation.
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Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Uveais
/
Neoplasias do Nervo Óptico
/
Melanoma
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acta Ophthalmol Scand
Assunto da revista:
OFTALMOLOGIA
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Noruega