Biotransformation of phenprocoumon in the rat.
J Med Chem
; 18(5): 519-23, 1975 May.
Article
em En
| MEDLINE
| ID: mdl-1151963
ABSTRACT
The metabolic fate of phenprocoumon [3-(alpha-ethylbenzyl)-4-hydroxycoumarin] in the rat is described. The major metabolites, 4',-6-,7-, and 8-hyproxyphenprocoumon, have been identified yb mass spectrometry, TLC, and uv and compared with authentic smaples. Metabolites are mainly excreted via the feces. The results are compared with those previously reported for warfarin.
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Bases de dados:
MEDLINE
Assunto principal:
Femprocumona
/
Cumarínicos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Med Chem
Assunto da revista:
QUIMICA
Ano de publicação:
1975
Tipo de documento:
Article