Oxidases responsible for resistance to pyrethroids sensitize Helicoverpa armigera (Hübner) to triazophos in West Africa.
Insect Biochem Mol Biol
; 33(9): 883-7, 2003 Sep.
Article
em En
| MEDLINE
| ID: mdl-12915179
ABSTRACT
Helicoverpa armigera (Hübner) is the major insect pest of cotton in Africa, Turkey, Asia, India, Indonesia and Australia. Populations recently developed resistance to pyrethroids in West Africa via the overproduction of cytochrome P450 (oxidases) increasing pyrethroid metabolism. One way to overcome pyrethroid resistance is to use compounds that show negative cross-resistance to pyrethroids. Triazophos is one of these compounds it is slightly more toxic against pyrethroid resistant larvae of H. armigera than against susceptible ones. Overproduced oxidases transform the non active triazophos into its active form, triazophos-oxon, since this form was significantly more often found in larvae from pyrethroid resistant strain (23%) than in susceptible strain (15%). This suggests that oxidases, which provide resistance by degradation of pyrethroids in the resistant individuals, also activate triazophos in its toxic oxon form resulting in a negative cross-resistance.
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Bases de dados:
MEDLINE
Assunto principal:
Compostos Organotiofosforados
/
Oxirredutases
/
Piretrinas
/
Triazóis
/
Resistência a Inseticidas
/
Inseticidas
/
Lepidópteros
Limite:
Animals
País/Região como assunto:
Africa
Idioma:
En
Revista:
Insect Biochem Mol Biol
Assunto da revista:
BIOLOGIA MOLECULAR
/
BIOQUIMICA
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
França