Lesion regression after percutaneous coronary intervention for unprotected left main trunk disease.
Int J Cardiovasc Intervent
; 5(3): 132-6, 2003.
Article
em En
| MEDLINE
| ID: mdl-12959729
ABSTRACT
BACKGROUND:
Although some studies have documented the six-month angiographic outcomes of percutaneous coronary intervention (PCI) with new devices for unprotected left main trunk disease (ULMTD), a long-term angiographic analysis is mandatory to evaluate the safety and effectiveness of this procedure. This study aims to assess a long-term (one year or more) angiographic analysis after PCI for this lesion.METHODS:
PCI was performed for 225 ULMTD with de novo or restenotic lesions. There were 19 deaths and 12 repeat PCIs during the hospital stay. The remaining 194 lesions were followed, and 126 lesions showed no angiographic restenosis or target lesion revascularization within six months. Finally, long-term quantitative angiographic follow-up was completed in 78 lesions (mean 2.4 years, maximum 7.5 years after PCI).RESULTS:
Minimal lumen diameter increased significantly from 2.46 +/- 0.59 mm to 2.72 +/- 0.65 mm (p < 0.0001) and percent diameter stenosis decreased significantly from 26 +/- 14% to 19 +/- 14% (p < 0.0001) between the six-month and the long-term follow-ups. No additional restenosis or new lesions were found at long-term follow-up, and significant lesion regression was ascertained in each procedure (directional coronary atherectomy, p < 0.005; ballooning, p < 0.005; stenting, p < 0.05).CONCLUSIONS:
These findings support the safety and effectiveness of PCI for ULMTD during the long-term period.
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Bases de dados:
MEDLINE
Assunto principal:
Complicações Pós-Operatórias
/
Angioplastia Coronária com Balão
/
Estenose Coronária
/
Reestenose Coronária
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Int J Cardiovasc Intervent
Assunto da revista:
CARDIOLOGIA
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Japão