Use of the mitral valve-tricuspid valve distance as a marker of fetal endocardial cushion defects.
Am J Obstet Gynecol
; 191(4): 1483-5, 2004 Oct.
Article
em En
| MEDLINE
| ID: mdl-15507987
ABSTRACT
OBJECTIVE:
The purpose of this study was to compare the mitral valve-tricuspid valve distance in second-trimester fetuses with normal cardiac anatomy versus those fetuses with endocardial cushion defects. STUDYDESIGN:
We identified fetuses between 16 and 24 weeks of gestation. The distance between the insertions of the medial leaflets of the mitral and tricuspid valves were obtained. Linear regression curves were generated.RESULTS:
The mean mitral valve-tricuspid valve distance for 86 fetuses with normal cardiac anatomy was 2.02 mm, compared with 0.37 mm in 13 fetuses with endocardial cushion defects ( P = .0001). Linear regression curve correlating mitral valve-tricuspid valve distance with gestational age showed a gradual slope (R 2 = 0.28; P < .0001). With a mitral valve-tricuspid valve distance < 5th percentile as a marker for the diagnosis of endocardial cushion defect gave a sensitivity of 69.2%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 95.6%, and a false-positive rate of 0% ( P = .0001).CONCLUSION:
The mitral valve-tricuspid valve distance is useful clinically in the detection of endocardial cushion defects in second-trimester fetuses.
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Bases de dados:
MEDLINE
Assunto principal:
Valva Tricúspide
/
Ultrassonografia Pré-Natal
/
Comunicação Atrioventricular
/
Doenças Fetais
/
Valva Mitral
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Am J Obstet Gynecol
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Estados Unidos