[Estrogen role in the luteal phase support in in vitro fertilization with embryo transfer cycles]. / Papel de los estrógenos en el soporte de la fase lútea en ciclos de fertilización in vitro con transferencia de embriones.
Ginecol Obstet Mex
; 72: 645-55, 2004 Dec.
Article
em Es
| MEDLINE
| ID: mdl-15813475
ABSTRACT
OBJECTIVE:
To evaluate the effectiveness of estradiol administration for luteal phase support and to describe the progesterone and estradiol behavior in vitro fertilization-embryo transfer luteal phase. MATERIAL ANDMETHODS:
Patients undergoing in vitro fertilization-embryo transfer with controlled ovarian hyperstimulation and using gonadotropin releasing hormone agonist. They were divided at random into two groups group 1 would receive progesterone alone, and group 2 would take estrogen and progesterone. Serum concentrations of estradiol and progesterone were measured on days 7 and 14 post-embryo transfer.RESULTS:
We examined 52 patients; 24 received progesterone alone and 28 took estrogen and progesterone. Significantly higher estradiol and progesterone concentrations on day 14 were found in pregnant women. It was not on day 7. A significant increment of estrogen was found in the estrogen and progesterone group. Progesterone did not increase significantly. Pregnancy rate was the same in both groups.CONCLUSIONS:
For patients undergoing in vitro fertilization-embryo transfer, the addition of estradiol to the progesterone support regimen does not have beneficial effects in terms of pregnancy rate. On day 7 neither progesterone nor estradiol are good predictors of pregnancy.
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Bases de dados:
MEDLINE
Assunto principal:
Progesterona
/
Gravidez
/
Fertilização in vitro
/
Transferência Embrionária
/
Estradiol
/
Fase Luteal
Limite:
Adult
/
Female
/
Humans
Idioma:
Es
Revista:
Ginecol Obstet Mex
Ano de publicação:
2004
Tipo de documento:
Article