Cortical reorganization of hand motor function to primary sensory cortex in hemiparetic patients with a primary motor cortex infarct.
Arch Phys Med Rehabil
; 86(8): 1706-8, 2005 Aug.
Article
em En
| MEDLINE
| ID: mdl-16084830
ABSTRACT
OBJECTIVE:
To show cortical reorganization in hemiparetic patients with a primary motor cortex (M1) infarct including the precentral knob by using functional magnetic resonance imaging (fMRI).DESIGN:
Case-control.SETTING:
Outpatient clinics in the rehabilitation department of a university hospital.PARTICIPANTS:
Two stroke patients and 20 control subjects.INTERVENTIONS:
By using fMRI, we evaluated the hand motor function of 2 hemiparetic stroke patients, who had made some recovery from complete paralysis of the affected hand, and 20 control subjects. MAIN OUTCOMEMEASURES:
fMRI was performed by using the blood oxygen level-dependent technique at 1.5 T with a standard head coil. The motor task paradigm consisted of hand grasp-release movements.RESULTS:
The contralateral primary sensorimotor cortex was activated by the hand movements of the control subjects and of the unaffected side of the 2 patients. Only the contralateral (infarct side) primary sensory cortex (S1) was activated by the movements of the affected hand of the 2 patients, a result that was not observed in the control subjects or with the unaffected hand in the stroke patients.CONCLUSIONS:
The hand motor function associated with the infarcted M1 in our patients was reorganized into the S1. These results suggest cortical reorganization in patients with an M1 infarct.
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Bases de dados:
MEDLINE
Assunto principal:
Paresia
/
Imageamento por Ressonância Magnética
/
Infarto Cerebral
/
Córtex Motor
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Arch Phys Med Rehabil
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Coréia do Sul