Methods for incorporating death into health-related variables in longitudinal studies.
J Clin Epidemiol
; 58(11): 1115-24, 2005 Nov.
Article
em En
| MEDLINE
| ID: mdl-16223654
ABSTRACT
BACKGROUND AND OBJECTIVES:
Longitudinal studies of health over time may be misleading if some people die. Self-rated health (excellent to poor) and the SF-36 profile scores have been transformed to incorporate death. We applied the same approaches to incorporate death into activities of daily living difficulties (ADLs), IADLs, mini-mental state examination, depressive symptoms, blocks walked per week, bed days, the timed walk, body mass index and blood pressure. STUDY DESIGN ANDSETTING:
The Cardiovascular Health Study of 5,888 older adults, was followed up to 9 years. Mean age was 73 at baseline, and 658 had an incident stroke during follow-up.METHODS:
We recoded each variable as the probability of being healthy 1 year in the future (PHF), conditional on the current value of the variable. This was done for 11 health variables, using three definitions of healthy, and two estimation models. Deaths were set to zero, and mean PHF was plotted in the 3 years before and after an incident stroke.RESULTS:
Analyses without the deaths were too optimistic. The effect of stroke was greatest on hospitalization, self-rated health, and IADLs. Alternative transformation approaches had slightly different results.CONCLUSION:
These methods provide an additional approach for handling death in longitudinal studies.
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Bases de dados:
MEDLINE
Assunto principal:
Indicadores Básicos de Saúde
/
Estudos Longitudinais
/
Morte
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
J Clin Epidemiol
Assunto da revista:
EPIDEMIOLOGIA
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos