Transprotection of silyl ethers of nucleosides in FeCl3 based ionic liquids.
Nucleosides Nucleotides Nucleic Acids
; 24(5-7): 819-22, 2005.
Article
em En
| MEDLINE
| ID: mdl-16248043
ABSTRACT
Ionic liquid mediated deprotection of tert-butyldimethyl silyl (TBDMS) ethers derived from various primary and secondary alcohols have been studied and the reaction conditions optimized. Deprotection of the silyl ethers in FeCl3 based ionic liquids in presence of acetic anhydride yielded the acetate esters of the corresponding alcohols in good yields. The transprotection methodology was extended to the silyl ethers of nucleosides to yield the corresponding acetylated products.
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Bases de dados:
MEDLINE
Assunto principal:
Compostos Férricos
/
Nucleosídeos
Idioma:
En
Revista:
Nucleosides Nucleotides Nucleic Acids
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2005
Tipo de documento:
Article