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[Results of FDG-PET scanning in the pre-operative staging of broncho-pulmonary tumors]. / Résultats de la TEP [18F]-FDG dans la stadification préopératoire des tumeurs pulmonaires.
Perrotin, C; Lemeunier, P; Grahek, D; Molina, T; Petino, A; Alifano, M; Bellenot, F; Magdeleinat, P; Talbot, J-N; Regnard, J-F.
Afiliação
  • Perrotin C; Service de Chirurgie Thoracique, Hôtel Dieu, Paris, France. cedric.perrotin@htd.ap-hop-paris.fr
Rev Mal Respir ; 22(4): 579-85, 2005 Sep.
Article em Fr | MEDLINE | ID: mdl-16294177
BACKGROUND: Positron emission tomography (PET) with [18F]fluorodeoxyglucose (FDG) has recently established itself as an important imaging strategy in the management of respectable non-small cell bronchial carcinoma (NSCLC). In this study we report our experience of the impact of FDG-PET in the pre-operative assessment of NSCLC. METHODS: In a single centre retrospective study between 01 January 2000 and 31 Dec 2002, 108 FDGPET scans were performed during the preoperative assessment of histologically proven or strongly suspected NSCLC. RESULTS: The sensitivity, specificity and accuracy of FDG-PET for the characterization of a parenchymatous opacity were 96%, 71% and 92% respectively (4 false negatives, 5 false positives). The sensitivity, specificity and accuracy for mediastinal node involvement were 62%, 94% and 84% respectively (10 false negatives and 4 false positives). The sensitivity, specificity and accuracy for the characterization of adrenal nodules were 88%, 100% and 97% (1 false negative) and for satellite pulmonary nodules 50%, 75% and 64% (2 false negatives and 3 false positives). CONCLUSION: FDG-PET is a useful imaging modality in the pre-operative management of NSCLC but is limited particularly in the characterization of lesions less than 10 mm in diameter and in the evaluation of mediastinal lymph nodes.
Assuntos
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Bases de dados: MEDLINE Assunto principal: Cuidados Pré-Operatórios / Carcinoma Pulmonar de Células não Pequenas / Compostos Radiofarmacêuticos / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: Fr Revista: Rev Mal Respir Ano de publicação: 2005 Tipo de documento: Article País de afiliação: França
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Bases de dados: MEDLINE Assunto principal: Cuidados Pré-Operatórios / Carcinoma Pulmonar de Células não Pequenas / Compostos Radiofarmacêuticos / Fluordesoxiglucose F18 / Tomografia por Emissão de Pósitrons / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: Fr Revista: Rev Mal Respir Ano de publicação: 2005 Tipo de documento: Article País de afiliação: França