Microcystin-RR-induced apoptosis in tobacco BY-2 cells.
Toxicon
; 48(2): 204-10, 2006 Aug.
Article
em En
| MEDLINE
| ID: mdl-16797632
ABSTRACT
Our previous studies showed that microcystin-RR could induce oxidative damage in plant cells as they do with animal cells. However, whether microcystin can induce plant cell apoptosis is still unknown. In this study, the morphological changes of tobacco BY-2 suspension cells exposed to microcystin-RR were observed under light microscopy and transmission electron microscopy, and apoptosis was clearly distinguished by intense perinuclear chromatin margination, condensation of nuclear chromatin after 6d exposure of 50mg/L (about 50microM) microcystin-RR. We also found that microcystin-RR can induce tobacco cell apoptosis in a dose- and time-dependent manner with flow cytometry analysis. Our study provides the first evidence that microcystins can induce plant cell apoptosis.
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Bases de dados:
MEDLINE
Assunto principal:
Peptídeos Cíclicos
/
Nicotiana
/
Cianobactérias
/
Apoptose
Idioma:
En
Revista:
Toxicon
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
China