Przewalskin A: A new C23 terpenoid with a 6/6/7 carbon ring skeleton from Salvia przewalskii maxim.
Org Lett
; 8(20): 4453-6, 2006 Sep 28.
Article
em En
| MEDLINE
| ID: mdl-16986923
ABSTRACT
Przewalskin A (1), a novel C23 terpenoid with a 6/6/7 carbon ring skeleton, was isolated from Salvia przewalskii. Its structure was determined by comprehensive 1D NMR, 2D NMR, and MS spectroscopic analysis and subsequently confirmed by a single-crystal X-ray diffraction study of its PDC oxidation derivative (2). Compounds 1 and 2 showed modest anti-HIV-1 activity with EC50 = 41 and 89 microg/mL, respectively.
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Bases de dados:
MEDLINE
Assunto principal:
Terpenos
/
Carbono
/
Cicloexanonas
/
Salvia
/
Diterpenos
Idioma:
En
Revista:
Org Lett
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2006
Tipo de documento:
Article