Vascular endothelial growth factor promoted endothelial progenitor cell mobilization into the peripheral blood of a patient with POEMS syndrome.
Haematologica
; 92(9): 1291-2, 2007 Sep.
Article
em En
| MEDLINE
| ID: mdl-17768134
ABSTRACT
We assessed the percentage of endothelial progenitor cells (EPCs) in the peripheral blood of a patient with POEMS with elevated VEGF plasma levels. High VEGF plasma levels were associated with increased EPC concentration and treatment with an anti-VEGF antibody induced a consensual decrease of both parameters. In vitro cultures of the patient BM cells suggested that the stromal compartment could be responsible for VEGF overproduction.
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Bases de dados:
MEDLINE
Assunto principal:
Células-Tronco
/
Endotélio Vascular
/
Movimento Celular
/
Síndrome POEMS
/
Fator A de Crescimento do Endotélio Vascular
Limite:
Humans
Idioma:
En
Revista:
Haematologica
Ano de publicação:
2007
Tipo de documento:
Article