Lichen planus pemphigoides associated with Chinese herbs.
Clin Exp Dermatol
; 34(3): 329-32, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-18699839
ABSTRACT
We report a 62-year-old Chinese woman with a 2-year history of lichen planus presenting with extensive violaceous maculopapules and plaques 1 week after taking an oral preparation of Chinese herbs. The patient developed vesiculobullous skin lesions 7 weeks later. Histopathological examination showed subepidermal blisters and adjacent bandlike lymphocytic infiltration. Direct immunofluorescence revealed linear deposits of IgG and C3 along the basement membrane zone. Indirect immunofluorescence showed IgG antibody deposition along the epidermal side of salt-split human skin. Circulating anti-bullous pemphigoid 180 antibodies were detected by ELISA. Lichen planus pemphigoides (LPP) was diagnosed. To our knowledge, this is the first report of LPP associated with oral Chinese herbs.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
/
Penfigoide Bolhoso
/
Toxidermias
/
Líquen Plano
/
Fitoterapia
Tipo de estudo:
Risk_factors_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Clin Exp Dermatol
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
China