Root coverage with cultured gingival dermal substitute composed of gingival fibroblasts and matrix: a case series.
Int J Periodontics Restorative Dent
; 28(5): 461-7, 2008 Oct.
Article
em En
| MEDLINE
| ID: mdl-18990997
ABSTRACT
Cultured gingival dermal substitute (CGDS), composed of gingival fibroblasts and matrix and fabricated using tissue-engineering techniques, has been used for root coverage procedures. Fourteen sites from four patients with > or = 2 mm of Miller Class I or II facial gingival tissue recession were treated. The autologous CGDS sheet, prepared prior to surgical treatment, was grafted over the teeth with gingival recession and then covered with a coronally positioned flap. Vertical and horizontal recession was measured at baseline (prior to the surgical procedure) and 13 to 40 weeks (average 30.7 +/- 9.6 weeks) after surgery. The average vertical and horizontal root coverage after surgery was 79.1% +/- 25.7% and 75.2% +/- 31.4%, respectively. Moreover, there was a significant increase of keratinized and attached gingival tissue at the final clinical evaluation compared with preoperative measurements (P < .05). These results demonstrate CGDS as a promising grafting material for use with root coverage procedures in periodontal therapy.
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Bases de dados:
MEDLINE
Assunto principal:
Raiz Dentária
/
Engenharia Tecidual
/
Alicerces Teciduais
/
Fibroblastos
/
Gengiva
/
Retração Gengival
Limite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Int J Periodontics Restorative Dent
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Japão