Ketogenic diet in Alpers-Huttenlocher syndrome.
Pediatr Neurol
; 40(4): 314-6, 2009 Apr.
Article
em En
| MEDLINE
| ID: mdl-19302948
ABSTRACT
We report on a young girl with Alpers-Huttenlocher syndrome, as confirmed by mitochondrial polymerase gamma sequencing, who was treated with the classic (4 parts fat1 part each of carbohydrate and protein) ketogenic diet after she presented with epilepsia partialis continua. She improved clinically, and her electroencephalogram improved dramatically. This is the first detailed report on the efficacy of the ketogenic diet in treating the epileptic encephalopathy of Alpers-Huttenlocher syndrome. We present a literature review of the utility of a ketogenic diet in mitochondrial disorders, and speculations as to why the diet may be helpful in Alpers-Huttenlocher syndrome.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Esclerose Cerebral Difusa de Schilder
/
Dieta Cetogênica
Limite:
Child, preschool
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Female
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Humans
Idioma:
En
Revista:
Pediatr Neurol
Assunto da revista:
NEUROLOGIA
/
PEDIATRIA
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Canadá