Profile order and time-dependent artifacts in contrast-enhanced coronary MR angiography at 3T: origin and prevention.
Magn Reson Med
; 62(2): 292-9, 2009 Aug.
Article
em En
| MEDLINE
| ID: mdl-19526488
ABSTRACT
To enhance the clinical value of coronary magnetic resonance angiography (MRA), high-relaxivity contrast agents have recently been used at 3T. Here we examine a uniform bilateral shadowing artifact observed along the coronary arteries in MRA images collected using such a contrast agent. Simulations were performed to characterize this artifact, including its origin, to determine how best to mitigate this effect, and to optimize a data acquisition/injection scheme. An intraluminal contrast agent concentration model was used to simulate various acquisition strategies with two profile orders for a slow-infusion of a high-relaxivity contrast agent. Filtering effects from temporally variable weighting in k-space are prominent when a centric, radial (CR) profile order is applied during contrast infusion, resulting in decreased signal enhancement and underestimation of vessel width, while both pre- and postinfusion steady-state acquisitions result in overestimation of the vessel width. Acquisition during the brief postinfusion steady-state produces the greatest signal enhancement and minimizes k-space filtering artifacts.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Algoritmos
/
Interpretação de Imagem Assistida por Computador
/
Aumento da Imagem
/
Angiografia Coronária
/
Artefatos
/
Angiografia por Ressonância Magnética
/
Vasos Coronários
/
Meglumina
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Magn Reson Med
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Estados Unidos