Primary cutaneous anaplastic large-cell lymphoma presenting with hemophagocytic syndrome: a case report and review of the literature.
Leuk Res
; 34(2): 263-6, 2010 Feb.
Article
em En
| MEDLINE
| ID: mdl-19640585
ABSTRACT
Primary cutaneous anaplastic large-cell lymphoma (C-ALCL) is a rare entity of lymphoma. We report a case of C-ALCL presenting with hemophagocytic syndrome and skin lesion with giant ulcer. Histopathological examination of the skin biopsy specimens showed non-epidermotropic infiltrates with cohesive sheets of large tumor cells. The tumor cells showed CD4-, CD8+, CD30+, CD56-, ALK-, TIA-1+, and granzyme B+. C-ALCL is generally a disorder that progresses slowly and has a good prognosis. Manifestation of a giant ulcer and hemophagocytic syndrome, such as in the present case, is rare.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Úlcera Cutânea
/
Linfoma Anaplásico de Células Grandes
/
Linfo-Histiocitose Hemofagocítica
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Leuk Res
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Japão