No association between oxytocin receptor (OXTR) gene polymorphisms and experimentally elicited social preferences.
PLoS One
; 5(6): e11153, 2010 Jun 16.
Article
em En
| MEDLINE
| ID: mdl-20585395
ABSTRACT
BACKGROUND:
Oxytocin (OXT) has been implicated in a suite of complex social behaviors including observed choices in economic laboratory experiments. However, actual studies of associations between oxytocin receptor (OXTR) gene variants and experimentally elicited social preferences are rare. METHODOLOGY/PRINCIPALFINDINGS:
We test hypotheses of associations between social preferences, as measured by behavior in two economic games, and 9 single nucleotide polymorphisms (SNPs) of the OXTR gene in a sample of Swedish twins (n = 684). Two standard economic games, the dictator game and the trust game, both involving real monetary consequences, were used to elicit such preferences. After correction for multiple hypothesis testing, we found no significant associations between any of the 9 single nucleotide polymorphisms (SNPs) and behavior in either of the games.CONCLUSION:
We were unable to replicate the most significant association reported in previous research between the amount donated in a dictator game and an OXTR genetic variant.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Comportamento Social
/
Receptores de Ocitocina
/
Polimorfismo de Nucleotídeo Único
/
Economia
Tipo de estudo:
Health_economic_evaluation
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
PLoS One
Assunto da revista:
CIENCIA
/
MEDICINA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Estados Unidos