Acute carbamazepine poisoning treated with resin hemoperfusion successfully.
Am J Emerg Med
; 29(5): 518-22, 2011 Jun.
Article
em En
| MEDLINE
| ID: mdl-20825822
ABSTRACT
Carbamazepine (CBZ) poisoning has been occurring more frequently. We describe the use of synthesized resin-absorbed hemoperfusion in the therapy of a 48-year-old man who developed carotic, cardiovascular shock and multiorgan dysfunction due to a CBZ overdose (the highest concentration of drug >20 mg/L; therapeutic range, 8-12 mg/L). The treatment was very successful; and the patient eventually was discharged with a full recovery and no complications, although his diagnosis and treatment had been delayed for 56 hours. Hemoperfusion has a steady clearance of this drug without subsequent rebound or potential hazards. Resin hemoperfusion should be first considered for acute CBZ intoxication, especially when drug-induced gastrointestinal hypomotility prevents elimination via the gut and patient is under life-threatening condition.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Carbamazepina
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Hemoperfusão
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Anticonvulsivantes
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Am J Emerg Med
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
China