Republished paper: Arterial stiffness in chronic kidney disease: causes and consequences.
Postgrad Med J
; 86(1019): 560-6, 2010 Sep.
Article
em En
| MEDLINE
| ID: mdl-20841331
ABSTRACT
Chronic kidney disease is associated with elevated cardiovascular risk, and heart failure and arrhythmias are the biggest causes of cardiovascular death in this population. Increased arterial stiffness is a hallmark of chronic kidney disease and is associated with adverse alterations in cardiac structure and function that may predispose to an increased risk of cardiovascular death. These changes are already apparent in early kidney disease, which is highly prevalent in the developed world. The mechanisms underlying increased arterial stiffness in chronic kidney disease are undoubtedly complex, but an understanding is paramount to enable the development of novel therapeutic strategies to prevent or reverse this pathophysiology and therefore reduce the cardiovascular disease burden in this high-risk cohort.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Arteriosclerose
/
Falência Renal Crônica
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Postgrad Med J
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Reino Unido