Percutaneous ultrasound-guided biopsies in the evaluation of thoracic tumours after PET-CT: a prospective diagnostic study.
Respiration
; 83(1): 45-52, 2012.
Article
em En
| MEDLINE
| ID: mdl-21934274
ABSTRACT
BACKGROUND:
Lesions detected by positron emission tomography-computed tomography (PET-CT) during the analysis of thoracic tumours are often impalpable at physical examination, and subsequent ultrasound (US) may aid in finding these lesions for pathologic evaluation.OBJECTIVES:
The success rate of percutaneous US-guided biopsies of palpable and non-palpable lesions and the impact on tumour stage were studied prospectively.METHODS:
Lesions, significant for diagnosis and disease stage, with metabolic activity on PET-CT and presumed appropriate for percutaneous approach under US guidance were selected for cytologic aspiration or tissue core biopsies.RESULTS:
In 127 patients, 134 lesions (subdivided into 24 local thoracic, 74 supraclavicular and 36 distant metastatic lesions) were biopsied percutaneously under US guidance. Malignancy, benign disease and inadequate biopsies were found in 80% (106/134), 14% (19/134) and 7% (9/134), respectively. In 55% (56/102) of patients, biopsies confirmed the disease stage. Fifty-one percent (18/35) of distant lesions and 54% (43/68) of supraclavicular lesions were impalpable on physical examination.CONCLUSIONS:
US-guided biopsies in patients with suspected thoracic malignancy on PET-CT provide an excellent tool for obtaining a pathological diagnosis, leading to a definitive disease stage in over half of the patients.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Neoplasias Torácicas
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Tórax
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Biópsia por Agulha
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Tomografia Computadorizada por Raios X
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Tomografia por Emissão de Pósitrons
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Imagem Multimodal
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Estadiamento de Neoplasias
Tipo de estudo:
Diagnostic_studies
/
Guideline
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Observational_studies
/
Prognostic_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Respiration
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Holanda