Minimotif Miner 3.0: database expansion and significantly improved reduction of false-positive predictions from consensus sequences.
Nucleic Acids Res
; 40(Database issue): D252-60, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-22146221
ABSTRACT
Minimotif Miner (MnM available at http//minimotifminer.org or http//mnm.engr.uconn.edu) is an online database for identifying new minimotifs in protein queries. Minimotifs are short contiguous peptide sequences that have a known function in at least one protein. Here we report the third release of the MnM database which has now grown 60-fold to approximately 300,000 minimotifs. Since short minimotifs are by their nature not very complex we also summarize a new set of false-positive filters and linear regression scoring that vastly enhance minimotif prediction accuracy on a test data set. This online database can be used to predict new functions in proteins and causes of disease.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Motivos de Aminoácidos
/
Bases de Dados de Proteínas
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Nucleic Acids Res
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Estados Unidos