Viperin, a key player in the antiviral response.
Microbes Infect
; 14(5): 419-26, 2012 May.
Article
em En
| MEDLINE
| ID: mdl-22182524
ABSTRACT
Viperin is an antiviral protein that is induced by different viruses, type I interferon, poly(IC) and lipopolysaccharide, which is localized to the endoplasmic reticulum and lipid droplets. Recently, our knowledge on the mechanism by which viperin inhibits viral replication has strongly increased. Interestingly, it also became clear that viperin can be used by viruses to increase their infectivity. Here, our current knowledge on the induction of viperin and its effect on virus replication will be reviewed.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Viroses
/
Proteínas
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Microbes Infect
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
MICROBIOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Holanda