Complete response of advanced hepatocellular carcinoma with multiple lung metastases treated with sorafenib: a case report.
Oncology
; 81 Suppl 1: 152-7, 2011.
Article
em En
| MEDLINE
| ID: mdl-22212950
ABSTRACT
Sorafenib, an oral multikinase inhibitor, has demonstrated clinical efficacy in patients with advanced hepatocellular carcinoma (HCC). However, in the SHARP trial (Sorafenib HCC Assessment Randomized Protocol trial) and the Asia-Pacific trial (conducted in the Asia-Pacific region), no cases of complete response (CR) were reported. Thereafter, only a relatively small number of CR cases were reported worldwide for sorafenib therapy. We herein report a case of CR in a patient treated with sorafenib for 4 months. The patient had advanced HCC with multiple lung metastases, and there has been no recurrence after 8 months following cessation of administration. To our knowledge, this is the first time a female treated with sorafenib alone for HCC has had a CR.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Piridinas
/
Benzenossulfonatos
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Carcinoma Hepatocelular
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Neoplasias Hepáticas
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Neoplasias Pulmonares
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Antineoplásicos
Tipo de estudo:
Clinical_trials
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Guideline
Limite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Oncology
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Japão