MicroRNA factory: RISC assembly from precursor microRNAs.
Mol Cell
; 46(4): 384-6, 2012 May 25.
Article
em En
| MEDLINE
| ID: mdl-22633486
ABSTRACT
RNA silencing requires assembly of an effector complex, RNA-induced silencing complex (RISC), composed of a small RNA and the Ago protein. In this issue of Molecular Cell, Liu et al. (2012) provide insights of miRNP/RISC assembly pathways in mammals, using an in vitro human RISC assembly assay programmed by pre-miRNAs.
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Bases de dados:
MEDLINE
Idioma:
En
Revista:
Mol Cell
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2012
Tipo de documento:
Article