Regenerative therapy for retinal disorders.
J Ophthalmic Vis Res
; 5(4): 250-64, 2010 Oct.
Article
em En
| MEDLINE
| ID: mdl-22737370
ABSTRACT
Major advances in various disciplines of basic sciences including embryology, molecular and cell biology, genetics, and nanotechnology, as well as stem cell biology have opened new horizons for regenerative therapy. The unique characteristics of stem cells prompt a sound understanding for their use in modern regenerative therapies. This review article discusses stem cells, developmental stages of the eye field, eye field transcriptional factors, and endogenous and exogenous sources of stem cells. Recent studies and challenges in the application of stem cells for retinal pigment epithelial degeneration models will be summarized followed by obstacles facing regenerative therapy.
Texto completo:
1
Bases de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
J Ophthalmic Vis Res
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Irã