Fabrication of a glucose biosensor based on citric acid assisted cobalt ferrite magnetic nanoparticles.
J Nanosci Nanotechnol
; 12(8): 6631-8, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-22962799
ABSTRACT
A novel and practical glucose biosensor was fabricated with immobilization of Glucose oxidase (GOx) enzyme on the surface of citric acid (CA) assisted cobalt ferrite (CF) magnetic nanoparticles (MNPs). This innovative sensor was constructed with glassy carbon electrode which is represented as (GOx)/CA-CF/(GCE). An explicit high negative zeta potential value (-22.4 mV at pH 7.0) was observed on the surface of CA-CF MNPs. Our sensor works on the principle of detection of H2O2 which is produced by the enzymatic oxidation of glucose to gluconic acid. This sensor has tremendous potential for application in glucose biosensing due to the higher sensitivity 2.5 microA/cm2-mM and substantial increment of the anodic peak current from 0.2 microA to 10.5 microA.
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Bases de dados:
MEDLINE
Assunto principal:
Compostos Férricos
/
Técnicas Biossensoriais
/
Cobalto
/
Ácido Cítrico
/
Nanopartículas Metálicas
/
Glucose
/
Magnetismo
Idioma:
En
Revista:
J Nanosci Nanotechnol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Índia