Major histocompatibility complex class II deficiency in Kuwait: clinical manifestations, immunological findings and molecular profile.
J Clin Immunol
; 33(3): 513-9, 2013 Apr.
Article
em En
| MEDLINE
| ID: mdl-23143406
ABSTRACT
Major Histocompatibility Complex (MHC) class II deficiency is a combined primary immunodeficiency disease that leads to overwhelming and recurrent infections. It was found to account for 19 % of combined immune deficiency cases in the National Primary Immunodeficiency Disorders Registry in Kuwait, a country with high prevalence of consanguinity. We present the clinical, immunologic and molecular features of 11 Kuwaiti patients who presented with MHC class II deficiency between 2004 and 2011.
Texto completo:
1
Bases de dados:
MEDLINE
Assunto principal:
Antígenos de Histocompatibilidade Classe II
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Imunodeficiência Combinada Severa
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Child
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Child, preschool
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Clin Immunol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Kuait